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Where the network stands

A leadership read on the whole investigator network — what's funded, what's moving, and what's been accomplished. Visible to CEO, Chair, and staff.

Next review · Thu, Oct 22

Active investigators

5

across 5 institutions

Candidates in pipeline

7

under Steering Committee review

Committed 2026–28

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2-year awards

Fall 2026 schedule

Steering Committee · Q3Tue, Sep 23, 2026 · 11:00 AM – 12:00 PM ETLeadership
Q4 Board MeetingWed, Oct 8, 2026 · 11:00 AM – 12:30 PM ETBoard
Investigator / SAB MeetingThu, Oct 22, 2026 · 10:00 AM – 2:00 PM ETInvestigators & SAB
Steering Committee · Q4Fri, Nov 20, 2026 · 11:00 AM – 12:00 PM ETLeadership

Board room

Board committee only

Financials, meeting recaps, and the draft board agenda — visible only to Board committee members.

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Recent accomplishments

  1. 2026 cycle

    Five FTD labs funded on 2-year awards

    Harper (Harvard), Wilfling (Max Planck), Walther (Sloan Kettering), Huang (WashU), and Herz (UT Southwestern) — all converging on lysosomal / endolysosomal dysfunction in FTD.

  2. Apr 2026

    First in-person network meeting (San Francisco)

    All five labs presented; two prospective PIs (Xuejun Jiang, Çağla Eroğlu) pitched; strategy sessions on translating science to therapeutics and building a self-sustaining nonprofit.

  3. Ongoing

    Shared platforms tie the network together

    Walther's lipidomics and Wilfling's cryo-ET support projects across all five labs, with a track record of joint publications.

  4. Jul 2026

    Research Steering Committee established

    Roy Parker, Hubert Chen, Bob Farese and Joachim Herz now conduct an initial review of investigator proposals before they reach the SAB. Seven candidates are in the pipeline.

Latest activity

    Nothing yet — activity appears here as people post and comment.

    Portfolio — current work

    Wade Harper, PhD

    Harvard Medical School

    Understanding FTD risk alleles through the lens of endolysosomal molecular profiles

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    Year 1 of 2

    Florian Wilfling, PhD

    Max Planck Institute for Biophysics

    Comparative lysosomal ultrastructure in FTD using cryo-electron tomography

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    Year 1 of 2

    Tobias Walther, PhD

    Sloan Kettering & Cornell

    Granulin-deficient FTD: disease mechanisms and intervention strategies

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    Year 1 of 2

    Eric J. Huang, MD, PhD

    Washington University in St. Louis

    TLR7 signaling in autoimmune dysfunction and neuroinflammation in FTD

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    Year 1 of 2

    Joachim Herz, MD

    UT Southwestern

    Progranulin as a secretory-pathway scaffold for lysosomal protein sorting

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    Year 1 of 2